James Chi-Ping Chen
Associate Research Scientist, Department of Dermatology, Columbia University
James Chen is a postdoctoral research fellow (Medical Genetics) jointly appointed in the labs of Andrea Califano (Systems Biology) and Angela Christiano (Genetics and Development). He recently completed his thesis work in the Califano Lab, where he designed and implemented an algorithm to infer the causal genetic driver mutations of glioblastoma using integrated patient-matched genomic (CNVs, methylation, SNPs), gene expression, and reverse-engineered transcriptional network data.
Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM, Califano A. Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks. Cell. 2014 Oct 9;159(2):402-14.
Higgins C, Chen JC, Cerise JE, Jahoda C, Christano AM. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair follicle growth. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19679-88.